STR Markers for Human Identification Essay Example | Topics and Well Written Essays - 1500 words

STR Markers for Human Identification - Essay Example As all living things contain DNA, and all DNA exhibits variability both among and within species, any biological material associated with a legal case carries in it information about its source (Mark A. Jobling e'tal).The major advantage of DNA based technique is requirement of very small amount of sample like drop of body fluid, cigarette butts , or hair is enough to determined the identity of criminal or person related to crime. There is almost century old history of forensic genetics started with human ABO blood group polymorphisms. It was used for quite long time but having few drawbacks it was not used quite frequently in present investigations. The major back trough occurred in 1984 when Alec Jeffreys identified the hyper variable loci known as MINISATELLITE. The banding pattern obtained from this micro satellite known as DNA fingerprinting and was widely used since it discovery. The only drawback of this system is complicated data and difficulty to interpret. Than Development of 'single-locus probes' (SLPs) here it revealed only a single, highly polymorphic, restriction fragment length polymorphism. And hence simplifying interpretation. In Typical SLP based investigation four SLPs were used successively to probe a Southern blot, yielding eight hyper variable fragments per individual.( Mark A. Jobling e'tal). ... Being sensitive, high discriminating power and reliable in case of mix sample qualifies STR as perfect forensic tool. Fig 1 shows chronologic evolution of forensic genetics (Nat Rev Genet. 2004 Oct; 5 (10):739-51.) STR (Short tandem repeat): STR, short tandem repeat are short sequences of DNA normally of length 2-5 base pairs. and one can fine numerous time repetition of these sequences. There are almost 10,000 published STR sequence available in different literature. most widely used STRs are tetra or penta tendon repeat as there are certain advantage of smaller repeat over larger one, like it can withstand DNA degradation and avoids preferential amplification during PCR. Similarly short repeat is getting attention in terms of genetic diseases like tri-nucleotide repeat associated Huntington disease. STR markers are mainly classified under two category 1) Autosomal STR and 2) Y-chromosomal STR. 1) Autosomal STR:Initially there were four simple STR were used but there were high probability of similar matching hence later on it raise two more Complex STR along with PCR assay targeted at the XY-homologous amelogenin genes. As Forensic experts realized the capability of STR based identification system more attention was provided toward development of standard technique. In this line four more loci were added in to the over all process and name as SGM plus. Based on this development effort were made to set up STR database to mention record of individual having crime history. There are some differences between the overall techniques employed for STR typing in different countries and legal systems. For example in USA FDI CODI Shaving 16

Philosophy Essay Example | Topics and Well Written Essays - 1250 words - 14

Philosophy - Essay Example apitalism in essence can be neither egalitarian nor authoritative, while Rawls felt that capitalism could afford basic rights and liberties to all while still allowing people to pursue their own desires. As these are contradictory viewpoint, they both cannot be correct. It is my position that Rawls’ theory is idealistic and doesn’t have much in common with the society in which we actually live, and that Kristol’s theory stands as the stronger of the two. Rawls’ basic conception of social justice is dependent upon two claims: 1) that people should have the most amount of personal liberty possible that is compatible with others’ and 2) that it is possible to arrange inequalities in regards to social and economic status so that can be to the advantages of all. Rawls’ position is an extrapolation of the idea of the social contract; the social contract is the idea that people enter into an agreement with each other and form a system by which they all agree to be governed. How Rawls’ idea differs is that he views justice as the that which is the product of the agreement, as opposed to a particular form of government. To differentiate his conception with previous ideas, he refers to his idea as ‘justice as fairness.’ Rawls feels that his two basic principles would be agreed upon by rational people. He feels that people, in order for his conception of social justice to work, must not be aware of their own individual assets, as far as natural abilities, dispositions, place in society, etc. This is where his idea of the ‘veil of ignorance’ comes in; the veil of ignorance makes everybody fair and equal, as there would be no way for a person to create an advantage over another through their own personal abilities. This would be most desirable because it would be the most fair, and any rational person would agree to enter into this sort of arrangement. In theory, this plan might sound ideal, but the problem is that there is no real life way to

The Tax Reform Act of 1986 Term Paper Example | Topics and Well Written Essays - 1250 words - 1

The Tax Reform Act of 1986 - Term Paper Example The tax reform act brought out two key ideas, which seemed as the motivation for the tax reform. The major idea in the tax reform act was fairness in the level of distribution of the tax burden or the overall level. The congress had considered pubic concerns of the high-income individuals who evaded tax payment and the large corporation that combine high book profits with little or no tax liability (Graetz 622). The act lowered income tax rates for both corporations and individuals. The changes in the tax reform act include changes in the time of settling of tax payments. The tax reform does not monitor some of the behavioural responses that change the tax system. This does question the tax reform of its revenue-neutral theme. The tax reform act did upset many established interests and practices, many lobbyists and constituents seeking to block the amending of the act gathered and organized grassroots’ campaigns to lobby against the tax reform act. The opposition of the act was also seen from the divided party control of the executive and the legislative branches. The tax reform act of the 1986 receives the praises of being the best example of a bipartisan tax reform in the American history. The act broadened the bases of both corporate and individual income taxes by getting rid of the various means of tax preferences. The top individual rate was reduced from 50 percent to 28 percent, and the top corporate tax rate decline was reduced from 48 percent to 34 percent. Prior to the passing of the tax reform act there existed a widespread disgust in the income tax system: there existed a prevalence of tax shelters this enabled the wealthy tax payers to escape much of their tax liability. The high tax rates also hampered the economic growth because it discouraged labour supply saving and investment. The tax code was complex this resulted in high compliance,

APA citation and zotero Essay Example for Free

APA citation and zotero Essay 1. A general â€Å"res earch s hows† type of statement that is supported by at least three different sources (e.g., three research articles) Zotero is an extension of Firefox web browser that enables users to save on books, article and other materials on which one is able to retrieve their citations (Morton, 2011; Vanhecke, 2008; Lewis, 2008)               2. A paraphrased sentence citing a single source with three to six authors Zotero retrieve and imports citation information from a number of sources such as newspaper, and commercial Web sites, and Web-based databases such as PubMed (Trinoskey, Brahmi, Gall, 2009, p. 225).                3. A subsequent sentence citing the same source as in Step 2 that correctly uses et al Air pollution is low in developed countries comapared to industrialised countries where it is high as evidenced by particular locations in Canada (Hystad et al, 2011, p. 1128).                4. A short quoted passage that is cited correctly. Make sure to include the page number and place the punctuation correctly He argues that, â€Å"Zotero’s note-taking feature is very practical. Users can enter small notes on a particular reference by simply typing in an input field. These notes are saved automatically and organized in conjunction with the citation information,† (Vanhecke, 2008, p. 275).                  5. A second quoted passage that is 40 words long or longer, which is formatted correctly as a block quote and cited correctly with the page number and punctuation placed correctly He explains how Zotero note taking works: Zotero’s note-taking feature is very practical. Users can enter small notes on a particular reference by simply typing in an input field. In addition, Zotero is integrated with Microsoft Word and other word processors and works in all computers formats (PC, Mac, and Linux). Features such as formatted citation export make it very simple for users to create a list of references in the perfect format desired for a manuscript or other use. Users can create a reference list by dragging and dropping citations, (Vanhecke, 2008 p. 275) References Hystad, P., Setton, E., Cervantes, A., Poplawski, K., Deschenes, S., Brauer, M., Demers, P. (2011). Creating National Air Pollution Models for Population Exposure Assessment in Canada. Environmental Health Perspectives, 119(8), 1128 Lewis, L. A. (2008). From the Front Lines: An Academic Librarian Reports on the Impact of APAs New Electronic References Guidelines. Reference User Services Quarterly, 48(2), 128-131. Morton, A. (2011). Digital Tools: Zotero and Omeka. Journal Of American History, 98(3), 952 Trinoskey, J., Brahmi, F. A., Gall, C. (2009). Zotero: A Product Review. Journal Of Electronic Resources In Medical Libraries, 6(3), 225. Vanhecke, T. E. (2008). Zotero. Journal Of The Medical Library Association, 96(3), 275 Source document

Reflective Essay of the Family

Reflective Essay of the Family Write a short autobiographical piece relating to the theories and concepts discussed in the first half of the course. How might parts of your own or your familys life observe, illuminate or be illuminated by the theories and concepts discussed in weeks 1-5 of the course? I was born in Italy and resided there till the age of twenty-eight. I lived in a regional town of around forty-thousand inhabitants with limited cultural opportunities. I studied for a baccalaureate in business and entered the working environment as a news cameraman. In Italy, this would be the equivalent of a blue-collar worker. After having been working for ten years I moved to London and commenced employment as a sales and account manager in I.T. This job required intellectual application to office administration and high degrees of interpersonal relations, combined with knowledge of the product and its application within the marketplace. My increased earnings allowed me to purchase a home for the first time. Access to cultural opportunities in London has broadened my knowledge and understanding of the arts. London has allowed me to realise my potential to become a professional and commence this process by undertaking a history degree. My experience of London has been one of inqui ry and integration within a tolerant and multicultural environment. I will now seek to observe and to illuminate by application to my life some of the concepts and theories discussed in the first half of the course. Conventional wisdom has redefined the social structure of society by cataloguing the population into three classes: the rich, the middle class and the poor. This is very likely to represent the current classification in Italy. Therefore, the distribution of income is the main factor why classes still exist through the buying and selling of labour.[1] In Italy, I would have been classified as being a member of the poor class. Italy is characterised by a stark division between highly industrialised districts and underdeveloped areas of peasant farming. However, it is not always the case that farmers are positioned in a lower economic class than those of white-collar workers. For instance, and from my own experience, Italian farmers may be economically better-off than public servants because of the potential to sell their produce in their ow n shops and to secure a higher income. Accordingly, their economic capital is directly converted in the form of property rights and tangible assets such as houses and cars. [2] By relocating to London my observable classification within a conventional understanding of class remained unchanged because I could only sell my skills and labour. Now applying Bourdieus frameworks for class in Italy, I would have been considered as having a low economic capital. However, Bourdieus concept of cultural and social capitals applied to my employment as a news cameraman demonstrates an enrichment of both those capitals due to the enlargement of my social contacts. It could be claimed that I had found the perfect fit and I was floating like a fish in water: my habitus, made up of layering built up by experiences grounded in my body and mind, had met a social world of which it is the product,[3] therefore, I was experiencing the world pleasantly and I was in my comfort zone. Being a newcomer in London brought about the experience of a downward shift on all my capitals. Work, education and social networks had to be rebuilt. When someone steps out of the comfort zone it is likely to resemble a fish out of water, a suffused sense of inadequacy.[4] The new environment has offered me opportunities to improve my education and expand my social contacts. Bourdieu suggests that it is under conditions of hysteresis[5] when you are a fish out of water that great changes can occur. The hysteresis effect might provide an explanation of how I can make sense of my new environment based on my habitus, and on my capacity to decode parallels between the previous context and the new one. The seven classes of the Great British Class Survey of 2013 are built upon the development of certain sectors of economic activity, such as the technical middle class and the new affluent workers.[6] In Italy I would have been included in the traditional working class. Using the Survey Calculator twice and ending up in two different classes, it was evident that I provided the same social and cultural capitals and only modified my income. Firstly, when I used to work as an account manager, I was assigned to the group of Established middle class, secondly, now that I am a student, I fall within the Traditional working class. Mike Savage, one of the promoters and researchers of the survey, in his BBC Radio 4 interview, has stated that the study has moved away from the occupational classes.[7] This would not be the case, in fact as the results of my two surveys demonstrate, it does not take into consideration cultural and social capitals. I also agree with Colin Mills, lecturer in sociol ogy at Nuffield College Oxford, that the nature of the BBC sample is somewhat flawed: the 160.000 respondents of the online survey are most likely to be more educated and in highly paid jobs, whereas the respondents of the face-to-face research of 1000 people are more varied and allowed to build more classes[8]. It can be claimed that the findings of the BBC survey come from the information provided by the smaller research, hence the internet survey plays almost no role in defining these categories and the class I fall in. It can be clearly observed that, by applying class theories to my own life, only one class theory demonstrates any depth of analysis with regards to social and cultural aspects, namely the one developed by Bourdieu. By moving from Italy to London, my class has shifted upwards in all my three capitals. References [1] https://www.marxists.org/archive/marx/works/1848/communist-manifesto/ch01.htm#007 [accessed on 20th January 2017] [2] Pierre, Bourdieu, The Forms of Capital, in John Richardson (ed.), Handbook of Theory and Research for the Sociology of Education, (New York, 1986),p.243 [3] Pierre, Bourdieu and LoiÃÅ'ˆc J. D., Wacquant, An invitation to reflexive sociology, (Cambridge, 1992),p.127 [4] Diane, Reay, Gill, Crozier and John, Clayton, (2010) Fitting in or standing out: working-class students in UK higher education, British Educational Research Journal 32(1),p.11 [5] Pierre, Bourdieu, Outline of a theory of practice, trans. Richard Nice, (Cambridge, 1977),p.78 [6] Mike, Savage et al., A new model of social class? Findings from the BBCs Great British Class Survey experiment, Sociology 47(2), p. 230 [7] http://www.bbc.co.uk/programmes/b07gg1kb [8] Ibid.

The Short Happy Life Of Francis Macomber by Ernest Hemingway Essay

The Short Happy Life of Francis Macomber In Ernest Hemingway's story, "The Short Happy Life of Francis Macomber," Francis Macomber, according to Hemingway, is a very unhappy man because of his cowardly display after facing a wounded lion and because of his inability to stand up to his wife. However, Francis Macomber regains his happiness and bravery while out hunting buffalo; unfortunately, it is short lived. Francis Macomber is a man in his mid-thirties, "very tall, very well built†¦ and considered handsome." He excelles at court games and has quite a number of big-game fishing records, yet, this morning he â€Å"has just shown himself to be a coward.†   Ã‚  Ã‚  Ã‚  Ã‚  The ordeal started the night before when Francis was awakened by the sound of a lion roaring, which frightened him for the rest of he night. In the early morning Francis, Margot (his wife) and their guide Robert Wilson go out to hunt for this lion. After coming upon the lion, Francis shoots three times, hitting it twice and only wounding it. The wounded lion went trotting off into the tall grass, hiding and waiting for the hunters to come after him. Before the men go in after the lion, Macomber sat, "sweating under his arms, his mouth dry, his stomach hollow feeling, wanting to find the courage to tell Wilson to go on and finish off the lion without him." As the men enter the tall grass, the lion came charging at them. The next thing he knows, Macomber is "running wildly, in panic in the open, running ...

technology in education :: essays research papers fc

Technology in Education With technology benefiting various fields, life has suddenly become a joyful journey for everyone. In the simple forms, like electronic stoves, telephones displaying caller’s ID and automobiles the ride of life has become a pleasure. In the same way, the lives of students have also taken a leap towards easiness. When we talk about technology in education the first and foremost advancement is the computer and internet. If a student has the Encyclopedia of Britannica or Microsoft’s Encarta Encyclopedia on his/her computer, he rarely finds himself in a library or even on the internet. But for those who don’t have these encyclopedias have the entire world of internet information at their finger-tips. Internet in its simplest form enables one to access emails; this too is a source of information especially for those who are in contact with their teachers and need constant aid. Those who have joined Distant Learning Education programs need internet and the snail-mail system. If the postage was unreliable or the money transfer system was unpredictable then distant learning programs wouldn’t be so famous and sought-after. A normal school going 8th grader has luxuries enough. Assignments are doable no matter how tough they are. If there is a presentation to go along with, then projectors come very handy. Children also bring along their self made slide shows if the facilities are favorable. The field of education is vast. Be it the education in cosmetics, graphic designing, journalism or multimedia, technology is playing a huge part. Take photography for instance; new models of cameras keep emerging, the film has a variety of types and now with the emergence of digital photography, many people have suddenly realized that they want to make it their profession. For this, institutes are bringing in latest course outlines, equipment for study, instructors are being brought-in and dark rooms are being built. Education was tough without technology. Parents were constantly worrying about their children who were sent abroad to study. Now with technology in picture, long distance calls have become much easier and considerably cheap. Nearly all students in an institute carry cell-phones making the above mentioned problem of worrisome parents seem small. Even though this involvement of mobile phone in the field of education is not that much, yet it’s so useful that just about everyone has this equipment. Taking lectures was tiresome task, but with the introduction gadgets like; PDA, laptop and voice recorders, this dull work is now more enjoyable.